With human serum albumin

HIGHLIGHTS

  • who: Metal Based Drugs et al. from the Faculty of Chemistry, University of Wroclaw, FJoliot Curie, Wroclaw, Poland have published the research: WITH HUMAN SERUM ALBUMIN, in the Journal: (JOURNAL)
  • what: In all the experiments a physiological buffer, pH 7.4 was used.

SUMMARY

    In recent years metal-based antitumor drugs have been playing a relevant role in antiblastic-chemotherapy, especially cis-DDP is regarded as one of the most effective anticancer drugs used in clinics. The principal regions of ligand binding_sites of albumin are located in hydrophobic cavities in subdomains . . .

     

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