Total synthesis and absolute configuration of the marine norditerpenoid xestenone

HIGHLIGHTS

  • who: Koichiro Ota from the School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Horinouchi, Hachioji have published the paper: Total Synthesis and Absolute Configuration of the Marine Norditerpenoid Xestenone, in the Journal: (JOURNAL)
  • what: The first total synthesis of xestenone has been accomplished via the stereocontrolled one-pot synthesis of cyclopentane derivatives using allyl phenyl sulfone as the key step.
  • how: Elemental analysis data were obtained using an Elemental Vavio EL.

SUMMARY

    The stereochemistry comprises two cis fused cyclopentane rings, as determined by the NOE correlation between . . .

     

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