Identification of an autologous insulin b chain peptide as target antigen for h-2kb-restricted

HIGHLIGHTS

  • who: Cytotoxic T Lymphocytes and colleagues from the Virginia University have published the research work: Identification of an Autologous Insulin B Chain Peptide as Target Antigen for H-2Kb-restricted, in the Journal: (JOURNAL) of 17/09/2022
  • what: The results presented in this study demonstrate that potentially autoreactive H-2Kb-restricted cytotoxic T_cells specific for an autologous insulin B chain peptide are present in the preimmune splenic T_cell repertoire.
  • how: Briefly this procedure is conducted as follows A constant excess amount of truncated peptide (10 #M) is added to 5tCr-labeled target . . .

     

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