HIGHLIGHTS
- who: from the Chronic rhinosinusitis (CRS) is characterised by persisting inflammation of the mucosa of the nasal cavity and paranasal sinusesCRS is a multifactorial disease associated with relapsing infections and causes a huge burden on health care systems (Bachert et al., ). To study the pathophysiology of CRS and host- pathogen interactions, traditional cell culture techniques are used. These use primary human nasal epithelial cells (HNECs) grown in submerged monolayers or at air liquid interface (ALI) and have been instrumental in studying basic and applied aspects of airway biology, disease and therapy (Ramezanpour et_al, have published the research . . .
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