HIGHLIGHTS
- who: Pin et al. from the National Taiwan University, Taiwan have published the research: The kingdom of the prolyl-isomerase Pin1: The structural and functional convergence and divergence of Pin1, in the Journal: (JOURNAL)
- what: As the authors investigate the different Pin1 orthologs across various species and diseases, using such conformation-specific antibodies could be a new area to explore in targeting Pin1-associated diseases.
- how: Experimental data showed that overexpression of the Pin1 PPIase domain alone could rescue the phenotype of ess1/ptf1 temperaturesensitive mutants (Zhou et_al 2000). This review proposes two . . .
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