HIGHLIGHTS
- who: Abris Gilvesy from the (UNIVERSITY) have published the paper: Spatiotemporal characterization of cellular tau pathology in the human locus coeruleus-pericoerulear complex by three-dimensional imaging, in the Journal: (JOURNAL)
- what: The authors demonstrate an intriguing morphological complexity and heterogeneity of AT8+ cellular structures in the LC representing various intracellular stages of NFT maturation and their diverse transition forms. The authors show that gradual dendritic atrophy is the first morphological sign of the degeneration of tangle-bearing neurons even preceding axonal lesions. The aim of this study is to explore the cytoarchitecture and tau . . .
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