Solution structure and interaction with copper in vitro and in living cells of the first bir domain of xiap

HIGHLIGHTS

  • who: Meng-Meng Hou from the (UNIVERSITY) have published the research: Solution structure and interaction with copper in vitro and in living cells of the first BIR domain of XIAP, in the Journal: (JOURNAL) of 16/Nov/2017
  • what: The authors characterize by NMR the structural properties of BIR1 in solution, and the effects of its interaction with copper both in_vitro and in physiological environments. In this study, using high-resolution NMR spectroscopy, the authors show that the BIR1 domain of human XIAP forms a homodimer in solution, in accordance with the X-ray_crystal_structure.
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