Acbd5 and vapb mediate membrane associations between peroxisomes and the er

HIGHLIGHTS

• who: JCB Report et al. from the University ofUK have published the research: ACBD5 and VAPB mediate membrane associations between peroxisomes and the ER, in the Journal: (JOURNAL) of 14/09/2022
• what: The authors show that ACBD5-VAPB interaction regulates PO-ER associations. The authors demonstrate that loss of PO-ER association perturbs PO membrane expansion and increases PO movement. The authors show the acyl-CoA-binding domain is not essential for PO-ER tethering, although the authors cannot exclude a role in modulating the interaction.
• how: Livecell imaging data were collected . . .
  

   

  

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