HIGHLIGHTS
- who: Glioblastoma and collaborators from the Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, USADepartment of Biophysics, Jagiellonian University, Krakow, Poland have published the Article: Cancer Drug Resistance, in the Journal: (JOURNAL)
SUMMARY
Whereas nNOS and eNOS operate at constitutive levels, require Ca2+ for activity, and produce low levels of NO ( and amp;lt; 0.1 μmol/L) in neurons and endothelial cells, iNOS does not require Ca2+, is induced by stress signals, e_g, in macrophages and neutrophils, and can generate much higher levels of NO (0.5-1 μmol/L)[11 . . .
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