Shiga toxin-bearing microvesicles exert a cytotoxic effect on recipient cells only when the cells express the toxin receptor

HIGHLIGHTS

  • who: Diana Karpman from the Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden, Université Paris-Saclay, CEA, INRAE, Médicaments et Technologies pour la Santé, (MTS), SIMoS, Gif-sur-Yvette, France have published the research work: Shiga Toxin-Bearing Microvesicles Exert a Cytotoxic Effect on Recipient Cells Only When the Cells Express the Toxin Receptor, in the Journal: (JOURNAL)
  • what: This prompted this study in which the authors aimed to investigate if the presence of Gb3 in microvesicles is sufficient for the induction of toxin-mediated cellular injury or if the recipient cell . . .

     

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