Three-dimensional collagen type i matrix up-regulates nuclear isoforms of the microtubule associated protein tau implicated in resistance to paclitaxel therapy in ovarian carcinoma

HIGHLIGHTS

  • who: Hilal Gurler and collaborators from the Department of Biopharmaceutical Sciences, University of Illinois at Chicago, South Wood Street have published the article: Three-Dimensional Collagen Type I Matrix Up-Regulates Nuclear Isoforms of the Microtubule Associated Protein Tau Implicated in Resistance to Paclitaxel Therapy in Ovarian Carcinoma, in the Journal: (JOURNAL)
  • what: Our data indicate up-regulation of tau expression in the specimens of metastatic ovarian carcinoma in comparison to those of the primary site.

SUMMARY

    Ovarian carcinoma is a spectrum of diseases of epithelial, stromal, and germ cell origins . . .

     

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