HIGHLIGHTS
- who: Joachim Pircher from the München, Ludwig-Maximilians-University, Munich, Germany have published the paper: Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The authors examine the role of cathelicidins in thrombotic and inflammatory conditions. The authors show that cathelicidins directly activate platelets and foster platelet-neutrophil interactions. The authors report here that hematopoietic LL-37/CRAMP induces platelet activation and secretion, which mediates platelet-leukocyte aggregate formation and neutrophil recruitment at sites of inflammation. The experiments were carried out in deep anesthesia as . . .
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