Hepatocyte growth factor/c-met signaling in head and neck cancer and implications for treatment

HIGHLIGHTS

  • who: Natalie J. Rothenberger and Laura P. Stabile from the Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA have published the research work: Hepatocyte Growth Factor/c-Met Signaling in Head and Neck Cancer and Implications for Treatment, in the Journal: (JOURNAL)
  • what: This study reported a nearly 40% increase in the HGF serum levels of R/M HNSCC patients compared to healthy controls and 23% increase in nonrecurrent patients compared with controls .
  • future: Xenograft models continue to provide an effective means for identifying inhibitors for further clinical development . . .

     

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