Hereditary diffuse gastric cancer: molecular genetics, biological mechanisms and current therapeutic approaches

HIGHLIGHTS

  • who: Lidia-Sabina Cosma and collaborators from the Department and Outpatients Department of Internal Medicine I, University Hospital Regensburg have published the research: Hereditary Diffuse Gastric Cancer: Molecular Genetics, Biological Mechanisms and Current Therapeutic Approaches, in the Journal: (JOURNAL)
  • what: The clinical phenotype of HDGC shows considerable heterogeneity with regard to the type of cancer and age of onset, rendering the identification of patients with a high pretest probability of HDGC challenging.
  • future: Future studies of genes associated with disease predisposition could focus on cancer genes with mild to moderate impact such as . . .

     

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