Modeling enzyme processivity reveals that rna-seq libraries are biased in characteristic and correctable ways

HIGHLIGHTS

• who: Nathan Archer from the School University of Warwick, Coventry , AL, UK have published the Article: Modeling Enzyme Processivity Reveals that RNA-Seq Libraries Are Biased in Characteristic and Correctable Ways, in the Journal: (JOURNAL) of November/23,/2016
• what: The authors show that the fairness of these assumptions varies within libraries: coverage by sequencing reads along and between transcripts exhibits characteristic protocol-dependent biases. The power of scRNA-seq to reveal cell population heterogeneity in transcriptome-wide fashion has made it the focus of intense recent research activity aimed at its further ün et_al . . .
  

   

  

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