The ephb4 receptor-tyrosine kinase promotes the migration of melanoma cells through rho-mediated actin cytoskeleton reorganization*

HIGHLIGHTS

  • who: Nai-Ying Yang from the (UNIVERSITY) have published the research work: The EphB4 Receptor-tyrosine Kinase Promotes the Migration of Melanoma Cells through Rho-mediated Actin Cytoskeleton Reorganization*, in the Journal: (JOURNAL) of October/27,/2006
  • what: Consistent with the data , there is increasing evidence that metastatic behavior in_vivo, the authors demonstrate a role for EphB4 receptor forward signaling in melanoma cell migration. The authors show that the EphB4 promotes melanoma cell migration through RhoA-mediated actin reorganization.
  • how: For this the authors used a kinase dead mutant that contains a single . . .

     

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