Structure of the human bk ion channel in lipid environment

HIGHLIGHTS

  • who: Lige Tonggu and Liguo Wang from the Department of Biological Structure, School of Medicine, University of Washington, Seattle, WA, USA have published the research: Structure of the Human BK Ion Channel in Lipid Environment, in the Journal: Membranes 2022, 758 of /2022/
  • what: Full-length human large conductance voltage- and calcium-activated potassium (hBK or hSlo1) channels were reconstituted into liposomes and the random spherically constrained (RSC) single-particle cryo-EM method was employed to determine its structure.
  • how: In this study hBK was reconstituted into liposomes and the lipid bilayer environment . . .

     

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