A computational diffusion model to study antibody transport within reconstructed tumor microenvironments

HIGHLIGHTS

• who: Ana Luísa Cartaxo from the (UNIVERSITY) have published the paper: A computational diffusion model to study antibody transport within reconstructed tumor microenvironments, in the Journal: (JOURNAL)
• what: To understand these interactions the authors propose a framework combining in vitro and in silico models. The authors show this platform can be used to generate random spatial distributions of the TME elements (tumor cell spheroids, fibroblasts and ECM fibers) inside the capsule, following a tunable stochastic approach. The authors developed a computational model that reproduces in silico antibody transport within a 3D in_vitro cancer model . . .
  

   

  

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