Fusion of docked membranes requires the armadillo repeat protein vac8p*

HIGHLIGHTS

  • who: Yong-Xu Wang from the Department of Biochemistry, University of Iowa, Iowa City, Iowa , have published the research work: Fusion of Docked Membranes Requires the Armadillo Repeat Protein Vac8p*, in the Journal: (JOURNAL)
  • what: The authors demonstrate that in Saccharomyces cerevisiae Vac8p a myristoylated and palmitoylated armadillo repeat is required for homotypic vacuole fusion. The authors propose that Vac8p may bind the fusion machinery through its armadillo repeats and that palmitoylation brings this machinery to a specialized lipid domain that facilitates bilayer mixing.

SUMMARY

    To examine trans-SNARE pairing in . . .

     

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