HIGHLIGHTS
- who: Tumor Angiogenesis and collaborators from the Oncology, Duke University Medical Center, Durham, North Carolina, United States of America, Nuclear Magnetic Resonance Research Group, Louvain Drug Research have published the article: Targeting the Lactate Transporter MCT1 in Endothelial Cells Inhibits Lactate-Induced HIF-1 Activation and Tumor Angiogenesis, in the Journal: (JOURNAL) of March/13,/2012
- what: The authors report that lactate stimulates HIF-1 activity in ECs, which directly accounts for angiogenesis independently of any additional pro-angiogenic stimulus. In the following experiments, the authors therefore examined the signaling effects of lactate added to . . .
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