Cannabidivarin alleviates neuroinflammation by targeting tlr4 co-receptor md2 and improves morphine-mediated analgesia

HIGHLIGHTS

  • who: Xue Wang from the The University of Tokyo, Japan have published the research: Cannabidivarin alleviates neuroinflammation by targeting TLR4 co-receptor MD2 and improves morphine-mediated analgesia, in the Journal: (JOURNAL)
  • how: This result is consistent with the experimental CETSA data.

SUMMARY

    Considering TLR4 is a XAMPs receptor for surveiling foreign substances in CNS, it would be interesting to explore whether CBDV acts as a XAMP and can be sensed by MD2, an accessory protein of TLR4 responsible for the recognition of ligand. The P-value was set at ## P . . .

     

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