HIGHLIGHTS
- who: Jia Ke and Lixin Zhu from the Affiliated Hospital, Guangdong Institute of Gastroenterology, Sun Yat-sen University, Guangzhou, China, Guangdong have published the paper: The Proinflammatory Role of Guanylate-Binding Protein 5 in Inflammatory Bowel Diseases, in the Journal: (JOURNAL)
- what: The authors show for the first time the elevated expression of GBP5 in colonic mucosa of patients with IBD and that GBP5 is required for the stimulated secretion of inflammatory cytokines and chemokines, including IL1β, from T lymphocytes and macrophages.
- how: The clustering result showed that GBP5 shared a similar expression . . .
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