A paradoxical role for regulatory t cells in the tumor microenvironment of pancreatic cancer

HIGHLIGHTS

  • who: Thomas Brouwer and colleagues from the Department of Surgery, Leiden University Medical Center, Albinusdreef, ZA Leiden, The Netherlands have published the Article: A Paradoxical Role for Regulatory T Cells in the Tumor Microenvironment of Pancreatic Cancer, in the Journal: Cancers 2022, 14, 3862. of /2022/
  • what: The authors show that Tregs associate with improved overall survival in PDAC patients.
  • how: The immunofluorescence procedures were tested in the presence of isotype controls. The following phenotypes were identified CD3+ CD8- FOXP3- T_cells (which were mainly comprised of CD4+ T helper cells) CD3+ CD8- FOXP3 . . .

     

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