Real-world evidence prediction of a phase iv oncology trial: comparative degarelix vs leuprolide safety

HIGHLIGHTS

  • who: JNCI Cancer Spectrum ( and collaborators from the DivisionAdministration, Silver Spring, MD, USA have published the paper: Real-World Evidence Prediction of a Phase IV Oncology Trial: Comparative Degarelix vs Leuprolide Safety, in the Journal: (JOURNAL) of March/17,/2022
  • what: This research emulates a randomized comparative safety study, the PRONOUNCE trial , which was designed to evaluate the comparative risk of major adverse cardiovascular events (MACE), defined as a composite of allcause mortality, nonfatal myocardial infarction, or nonfatal stroke, among advanced prostate cancer patients treated with androgen_deprivation_therapy. The trial was intended to address conflicting reports . . .

     

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