Plcg2 is associated with the inflammatory response and is induced by amyloid plaques in alzheimer’s disease

HIGHLIGHTS

• who: Andy P. Tsai from the Department of Radiology and Imaging Sciences, Indiana University School have published the research work: PLCG2 is associated with the inflammatory response and is induced by amyloid plaques in Alzheimer’s disease, in the Journal: (JOURNAL)
• what: The analysis showed a disease progression-dependent increase in Plcg2 expression in mice with amyloid pathology. The authors report that PLCG2 expression is increased in several brain regions of LOAD patients and that increased PLCG2 expression levels positively correlate with both brain amyloid plaques and expression levels of microglial marker genes (AIF1 and . . .
  

   

  

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