Poly (n-vinylpyrrolidone) modification mitigates plasma protein corona formation on phosphomolybdate-based nanoparticles

HIGHLIGHTS

  • who: Youyi Yu from the State Key Laboratory of Oncogenes and Related Genes, Institute Jiao Tong University, Shanghai, China have published the Article: Poly (N-vinylpyrrolidone) modification mitigates plasma protein corona formation on phosphomolybdate-based nanoparticles, in the Journal: (JOURNAL)
  • what: Experimental and methods Reagents Keggin-type phosphomolybdic acid H ­ 3PMo12O40.xH2O ­(PMo12), sodium dodecyl sulfate (SDS), cesium carbonate ­(Cs2CO3), Polyvinylpyrrolidone (PVP K30, average Mw: 300 000) were obtained from Alfa Aesar.

SUMMARY

    The nanoparticles (NPs) tend to undergo nonspecific protein adsorption (formation of "protein corona") when entering the physiological system . . .

     

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