Interaction of thymine dna glycosylase with oxidised 5-methyl-cytosines in their amino- and imino-forms

HIGHLIGHTS

  • who: Firstname Lastname and collaborators from the Department of Physics, Freie Universität Berlin, Arnimallee, Berlin, GermanyComputer Chemistry Centre, Department for Chemistry and Pharmacy, Friedrich-Alexander University have published the research work: Interaction of Thymine DNA Glycosylase with Oxidised 5-Methyl-cytosines in Their Amino- and Imino-Forms, in the Journal: Molecules 2021, 26, 5728. of /2021/
  • what: By means of molecular simulations, the authors compare these DNA systems, in free form and complexed to TDG, so as to explore the differences in conformational dynamics and protein-DNA interactions between the different oxidised forms and . . .

     

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