HIGHLIGHTS
- who: He-Ping Ma from the (UNIVERSITY) have published the research work: Anionic Phospholipids Regulate Native and Expressed Epithelial Sodium Channel (ENaC)*, in the Journal: (JOURNAL) of December/17,/2001
- what: This study aims to determine whether anionic phospholipids such as PIP2, PIP3, and PS regulate ENaC activity. This study shows that anionic phospholipids activate endogenously expressed ENaC in A6 cells and exogenously expressed ENaC in Xenopus oocytes. It appears that aldosterone-mediated activation of sgk kinase rapidly stimulates translocation of ENaC to the apical membrane , while the experiments described in the legend to Fig . . .
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