Distribution and inter-regional relationship of amyloid-beta plaque deposition in a 5xfad mouse model of alzheimer’s disease

HIGHLIGHTS

  • who: Man-Lung Fung and You-qiang Song and Lee Wei Lim from the Chinese Culture University, Taiwan have published the research: Distribution and inter-regional relationship of amyloid-beta plaque deposition in a 5xFAD mouse model of Alzheimer's disease, in the Journal: (JOURNAL)
  • what: The experiment was conducted as previously described to evaluate locomotor function (Lim et_al, 2016; Tan et_al, 2020b). The authors showed 9-month-old adult 5xFAD mice had significantly impaired spatial learning and memory functions.
  • how: The transgenic 5xFAD mouse model was developed in 2006 to study lateonset . . .

     

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