Protein kinase c-related kinase and rock are required for thrombin-induced endothelial cell permeability downstream from gα12/13 and gα11/q*

HIGHLIGHTS

• who: Julie Gavard from the (UNIVERSITY) have published the research: Protein Kinase C-related Kinase and ROCK Are Required for Thrombin-induced Endothelial Cell Permeability Downstream from Gα12/13 and Gα11/q*, in the Journal: (JOURNAL) of October/31,/2008
• what: The authors show that thrombin signals through PAR-1 and its coupled G proteins G␣12/13 and G␣11/q to induce RhoA activation and intracellular calcium elevation, and that these events are interrelated. Whereas pro- 29888 JOURNAL OF BIOLOGICAL CHEMISTRY This is an Open Access article under the CC BY . . .
  

   

  

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