Dysregulation of sirt3 sumoylation confers aml chemoresistance via controlling hes1-dependent fatty acid oxidation

HIGHLIGHTS

  • who: Yirong Zhang and collaborators from the Department of Biochemistry and Molecular Cell Biology, Shanghai Tong University School of Medicine, Department of Biological Science, School of Life Science, Shaanxi Normal University, Xi'an, China have published the paper: Dysregulation of SIRT3 SUMOylation Confers AML Chemoresistance via Controlling HES1-Dependent Fatty Acid Oxidation, in the Journal: (JOURNAL)
  • what: This study revealed a novel role of in the regulation of in HES1-dependent FAO and provided a rationale for and FAO targeted interventions to improve chemotherapies in The study demonstrated that inhibition of SENP1 by momordin-Ic . . .

     

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