HIGHLIGHTS
- who: Rong Tang from the Duke University, United States have published the Article: Negative regulation of receptor tyrosine kinases by ubiquitination: Key roles of the Cbl family of E3 ubiquitin ligases, in the Journal: (JOURNAL)
- future: Research is still required to fully understand the underlying molecular mechanisms of the Cbl family in the regulation of RTKs which may provide new clues to clinical applications in the future. domain associates directly with the tyrosine residues in autophosphorylated EGFR and Grb2 also binds to other RTKs such as HGFR .
SUMMARY
Receptor tyrosine kinases . . .
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