Sex and apoe genotype alter the basal and induced inflammatory states of primary microglia from apoe targeted replacement mice

HIGHLIGHTS

• who: Isha Mhatre-Winters et al. from the Department of Environmental Health Sciences, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL, USA have published the research: Sex and APOE Genotype Alter the Basal and Induced Inflammatory States of Primary Microglia from APOE Targeted Replacement Mice, in the Journal: (JOURNAL) of 29/08/2022
• what: The authors assess the responses of and sex-specific APOE3 and APOE4 primary microglia (PMG) to lipopolysaccharide and interferon-gamma. In the investigation inflammatory cytokine profiles were assessed by qPCR and multiplex ELISA assays. The . . .
  

   

  

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