Invariant surface glycoprotein 65 of trypanosoma brucei is a complement c3 receptor

HIGHLIGHTS

• who: Olivia J. S. Macleod from the (UNIVERSITY) have published the article: Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor, in the Journal: (JOURNAL) of 19/09/2021
• what: The authors demonstrate that an invariant surface glycoprotein, ISG65, is a receptor for complement component 3 (C3). The authors show how ISG65 binds to the thioester domain of C3b. The experiment in which C57BL/6J or C57BL/6J C3-/- mice were infected with ISG65-/- trypanosomes (Fig 4c) was conducted subsequently and, although the same trypanosome cell line was used as above, should . . .
  

   

  

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