Fixed-parameter tractable sampling for rna design with multiple target structures

HIGHLIGHTS

  • who: Sebastian Will from the (UNIVERSITY) have published the Article: Fixed-Parameter Tractable Sampling for RNA Design with Multiple Target Structures, in the Journal: (JOURNAL)
  • what: As central contribution, the authors provide a systematic and flexibly extensible technique for sampling that targets multiple versatile features. The authors show that a specialization of the core problem, namely the enumeration of designs that respect canonical base_pairing rules (A ↔ U, G ↔ C, G ↔ U) is #P-hard, even when the dependency graph is bipartite and connected. The authors show that is bijective:. is injective, i.e. (f )=(f . . .

     

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