HIGHLIGHTS
- who: Edda G. Schulz and colleagues from the CNRS UMR, INSERM, Paris, France have published the research work: Rnf12—A Jack of All Trades in X Inactivation?, in the Journal: (JOURNAL) of January/27,/2011
SUMMARY
The X chromosome inactivation network. (A) Xist expression is controlled by counteracting activators (red) and repressors (blue). Stem cell factors (blue ovals) might repress Xist directly or indirectly via activating the repressive transcript Tsix or repressing the activator Rnf12. Rnf12 is the only known activator, and may function by targeting the Xist promoter directly and/or by . . .
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