A new class of multimerization selective inhibitors of hiv-1 integrase

HIGHLIGHTS

  • who: HIV- et al. from the Center for Retrovirus Research and College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America, Division of Medicinal Chemistry and have published the article: A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase, in the Journal: (JOURNAL) of May/29,/2014
  • what: The authors report design of small molecules that allowed the authors to probe the role of HIV-1 IN multimerization independently from IN-LEDGF/p75 interactions in infected cells. The authors report the design of pyridine-based small_molecules that contain a rotatable . . .

     

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