Low-level regulatory t-cell activity is essential for functional type-2 effector immunity to expel gastrointestinal helminths

HIGHLIGHTS

• who: K A Smith from the MiceBALB/c and C BL/, mice were bred in house under specific pathogen-free conditions. Foxp3.Luci, mice previously described26, were re-derived on a BALB/c and C BL/, background at the University of Edinburgh. BALB/c DEREG mice were also used as described [88]. All protocols were approved by the University of Edinburgh's Ethical Review Committee and all animal work was conducted under UK Home Office licence. DTx was administered intraperitoneally (i.p.) to Foxp GFP-negative and, positive littermates at a dose of , ng g have published . . .
  

   

  

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