Cysteine mutants of the major facilitator superfamily-type transporter ccoa provide insight into copper import

HIGHLIGHTS

  • who: B.K. Hassani and collaborators from the of Biology, University of Pennsylvaniagrid2587931, Philadelphia, Pennsylvania, USA have published the research work: Cysteine Mutants of the Major Facilitator Superfamily-Type Transporter CcoA Provide Insight into Copper Import, in the Journal: (JOURNAL)
  • what: The authors show that undergoes thiol:disulfide oxidoreduction cycle which important for its Cu activity. The experiments were conducted as described in Fig 5, except that E. coli cells expressing the native (left side panels) and double mutant variants of CcoA were used: C49AC247A (A), C247A-C367A (B), C49A-C109A (C), C109A-C367A (D . . .

     

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