Profiling microglia from alzheimer’s disease donors and non-demented elderly in acute human postmortem cortical tissue

HIGHLIGHTS

  • who: Bart J. L. Eggen from the Department of Biomedical Sciences of Cells and Systems, Section Molecular Neurobiology, University of Groningen, Copenhagen, Copenhagen, Denmark have published the research work: Profiling Microglia From Alzheimer's Disease Donors and Non-demented Elderly in Acute Human Postmortem Cortical Tissue, in the Journal: (JOURNAL)
  • what: The study was focused on cell-type specific responses to AD development, and profiling of ~50 microglia per donor was insufficient to fully define microglia diversity in AD. The authors aimed to identify transcriptomic changes in human microglia at the end stage of AD . . .

     

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