Mechanistic insights into global suppressors of protein folding defects

HIGHLIGHTS

  • who: Gopinath Chattopadhyay et al. from the Regenerative Medicine, Bangalore, India Editor:, Uppsala University have published the article: Mechanistic insights into global suppressors of protein folding defects, in the Journal: (JOURNAL) of August/29,/2022
  • what: The authors show here that thermodynamic stabilisation is neither necessary nor sufficient for suppressor action. The relevant to the figures in the paper have been made available within the article and in the supplementary information section. The authors characterized the global suppressor M182T and observed its effect on stability and folding of known inactive mutants (Fig 3). The authors . . .

     

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