HIGHLIGHTS
- who: Jonathan Boucher and colleagues from the CNRS ERL, Laboratoire "Signalisation and Transports Ioniques Membranaires", University of Poitiers, CHU de Poitiers, Poitiers, France have published the article: Pannexin-1 in Human Lymphatic Endothelial Cells Regulates Lymphangiogenesis, in the Journal: (JOURNAL)
- what: The authors show using primary human dermal lymphatic endothelial cells (HDLECs) pharmacological tools (probenecid Brilliant Blue FCF mimetic peptides ) and siRNA-mediated knockdown that Pannexin-1 is necessary for capillary tube formation on Matrigel and for VEGF-C-induced invasion. The work shows that PANX1 knockdown did not change the proliferative rate of HDLECs . . .
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