HIGHLIGHTS
- who: Darren K. McGuire from the Division of Cardiology, University of Texas Southwestern Medical Center, ‑8830, USA have published the research work: Transitioning to active-controlled trials to evaluate cardiovascular safety and efficacy of medications for type 2 diabetes, in the Journal: (JOURNAL)
- what: This approach has the advantage of a smaller sample size and/or shorter duration of the trial. This approach has been used previously in posthoc analyses of direct oral anticoagulants (DOAC) versus warfarin trials to assess the superiority of DOACs versus imputed placebo , and related statistical methods and limitations have been . . .
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