Tumor antigenicity and a pre-existing adaptive immune response in advanced braf mutant colorectal cancers

HIGHLIGHTS

  • who: Elena Bolzacchini and colleagues from the Oncology Department, Sant'Anna Hospital, ASST-Lariana, Como, Italy, University of Insubria, Varese, Italy have published the paper: Tumor Antigenicity and a Pre-Existing Adaptive Immune Response in Advanced BRAF Mutant Colorectal Cancers, in the Journal: Cancers 2022, 14, x FOR PEER REVIEW of /2022/
  • what: By contrast the APM signature was significantly upregulated in CD8+ BRAF-CRCs versus the study demonstrates that a significant fraction of BRAF-CRCs may be a candidate for immunotherapy and that the simultaneous analysis of MSI status and CD8+ TIL content increases . . .

     

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