Activation of acvr1-mediated signaling results in semilunar valve defects

HIGHLIGHTS

• who: Shabber Syed and colleagues from the Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI, USA have published the article: Activation of AcvR1-Mediated Signaling Results in Semilunar Valve Defects, in the Journal: (JOURNAL)
• what: This work shows that in a mouse model such continuous AcvRI activity in the Nfatc1Cre recombination domain results in pathological changes in the aortic structure and function. The authors show that Acvr1 is expressed in several cardiac cell types in postnatal mice, and that activation of AcvRI in the Nfatc1Cre recombination domain (endocardium . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.