HIGHLIGHTS
- who: Aurélie Ponceau and collaborators from the Santé, Grenoble, France have published the Article: αII-Spectrin Regulates Invadosome Stability and Extracellular Matrix Degradation, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0120781]. April 1, 2015 of September/29,/2014
- what: The study investigated the function of a poorly known component of invadosomes, αII-spectrin. The authors demonstrate the presence of αII-spectrin in invadosomes from HMEC-1 and HUVEC endothelial cells stimulated by phorbol ester (PMA) and in MEF cells transformed by SrcY527F. The experiments show that αII-spectrin silencing is associated . . .
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