Regulation of the mutually exclusive exons 8a and 8 in the cav1.2 calcium channel transcript by polypyrimidine tract-binding protein*

HIGHLIGHTS

  • who: Zhen Zhi Tang from the (UNIVERSITY) have published the research: Regulation of the Mutually Exclusive Exons 8a and 8 in the CaV1.2 Calcium Channel Transcript by Polypyrimidine Tract-binding Protein*, in the Journal: (JOURNAL) of March/25,/2011
  • how: PTB and nPTB are highly similar in peptide sequence and have similar RNA-binding properties and yet the authors have found a group of exons including exon 8a that are differentially affected by the two proteins.
  • future: More work is needed to identify the larger set of regulatory factors and sequence elements . . .

     

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