Access to original vinylic chlorides in the quinazoline series via a monoelectronic transfer reaction approach

HIGHLIGHTS

• who: Martine Maillard-Boyer from the Laboratoire de Pharmacochimie Radicalaire, Faculté de Pharmacie, Universités I, II have published the research: Access to Original Vinylic Chlorides in the Quinazoline Series via a Monoelectronic Transfer Reaction Approach, in the Journal: Molecules 2010, 15, 2719-2729 of 26/01/2010
• what: Quinazoline derivatives are molecules with a high pharmaceutical potential, particularly when targeting kinases.
• how: The results showed that the phase transfer conditions of Norris gave the best reaction yield. The results showed that the reaction obeys to a radical pathway in particular when comparing . . .
  

   

  

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