HIGHLIGHTS
- who: Tatsuro Noguchi and collaborators from the Department of Physiological Chemistry, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan have published the paper: CCRK/CDK20 regulates ciliary retrograde protein trafficking via interacting with BROMI/TBC1D32, in the Journal: PLOS ONE of 28/09/2021
- what: The authors characterized the interaction of CCRK/CDK20 with BROMI/TBC1D32. For the following reasons, it is likely that CCRK regulates ciliary protein trafficking via activating ICK or promoting its trafficking to the ciliary tips: CCRK phosphorylates ICK at its TDY motif ; phosphorylation of an ICK ortholog . . .
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