Cell type-specific role of rna nuclease smg6 in neurogenesis

HIGHLIGHTS

  • who: Gabriela Maria Guerra and colleagues from the Leibniz Institute on Aging-Fritz Lipmann Institute (FLI), Beutenbergstr, Jena, GermanyFaculty of Biological Sciences, Friedrich-Schiller University of Jena, Beutenbergstr, Jena, Germany have published the paper: Cell Type-Specific Role of RNA Nuclease SMG6 in Neurogenesis, in the Journal: Cells 2021, 10, x FOR PEER REVIEW of /2021/
  • what: SMG6 Null Mutation Activates DNA Repair and p53 Pathways Causing Cell Cycle 12 of 19 Taken together, using two different neural specific Cre mouse models, the authors demonstrate that GE NPCs and interneurons are particularly vulnerable to SMG6 . . .

     

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